Finding a relatively low risk for a variety...

BV is very common among women of reproductive age, but for general condition, the subsequent risk of adverse effects pregnancy

small (,

). Finding a relatively low risk for a variety of activities may actually be due to inaccurate determination of exposure. As mentioned earlier, BV syndrome with the degree of positivity. modern literature studied Communications Communications between the

BV positivity and health, but currently we do not know the studies that examined the body specific risks for disease. In addition, it is unclear whether BV is a risk factor for disease or exposure to BV or different microorganisms

cause inflammatory changes to event prediction of adverse effects. We know that BV diagnosed >> << lower genital tract was associated with 1) increase the potential for other vaginal pathogens to access to the top

genital tract, 2) the presence of enzymes that reduces the ability of leukocytes to reduce infections, and 3) increase the level of endotoxin >> << stimulating cytokine and prostaglandin production (

BЂ " ). In fact, Imseis al. reported higher levels of vaginal interleukin-1 beta, inflammatory cytokines, including pregnant women

BV, and Spandorfer et al. and found higher levels of cervical interleukin-1 beta and interleukin-8 levels of cytokines in

non-pregnant women with BV (,

). Future studies should try to define BV BV impact and identify inflammatory effects of BV and

risk of adverse effects of pregnancy. The next section discusses research conducted to date studying strattera dosing the role of BV and pregnancy outcome.

The vast majority of epidemiological studies aimed at studying the role of BV and adverse effects of pregnancy

focused on the risk of preterm birth, although many of these studies incorrectly combined preterm birth and preterm, premature rupture of membranes in

. In any case, these studies consistently show twice increased risk of preterm delivery >> << women diagnosed with BV, especially BV diagnosed in the early second trimester (,,

). A recent meta-analysis of studies on the consideration of the role of BV and the risk of preterm delivery reported a summary odds ratio of 1

. 6, indicating a 60 percent increase risk of preterm delivery in pregnant women with BV. Fewer studies

rated the relationship between BV and the results of premature birth, low birth weight and premature rupture of membranes

. One research study several outcomes of pregnancy associated with BV diagnosed during the first trimester of pregnancy

reported 2. 6-fold increased risk of preterm delivery (95 percent confidence interval. 1. 3, 4, 9), 6. 9-fold increased risk of premature birth >> << (95 percent confidence interval. 2. 5, 18 August), 7. 3-fold increased risk of preterm, premature rupture of membranes >> << (95 percent confidence interval. 1. 8, April 29) (

). Another study found that BV diagnosed in the second trimester of pregnancy was associated with an increased risk of preterm delivery

and premature rupture of membranes and BV is 83 percent relative risk of preterm delivery (

). The growing volume of literature began to suggest an increased risk of spontaneous abortion in pregnant women with BV

(,,

). The study was reported in three to five times increased risk of spontaneous abortion in pregnant women with BV in the first trimester >> << although these studies were small sample size prevents (,

). Two additional studies among high-risk pregnant women also reported an increase in spontaneous abortion in women diagnosed with

with BV (,

). The research register of women who undergo infertility treatment discovered more than two times increase the risk of spontaneous abortion >> << women with BV after adjustment for maternal age, with livebirth, and most reported smoking (relative risk

= 2. 67, 95-percent confidence interval. 1. 26, 5 63) (

). Numerous clinical studies have examined the effectiveness of oral and local treatment of BV to reduce the risk of preterm delivery >> << and found no risk reduction among pregnant women receiving treatment with topical BV (,

). Although arguably, the oral therapy offered various therapeutic approaches for the symptomatic, asymptomatic

, and high-risk pregnant women. Symptomatic pregnant women with BV are considered to relieve symptoms and prevention

side effects (eg, preterm labor, preterm labor, premature rupture of membranes) is desirable, but not well documented

(

). Treatment of asymptomatic BV-positive pregnant women and may reduce the adverse effects of pregnancy and

unclear. Three separate placebo-controlled randomized clinical trials indicate a reduced risk of preterm birth after treatment

metronidazole, however, in two studies, the reduction was found in only a small portion of high risk

asymptomatic pregnant women (

BЂ "). Indeed, the meta-analysis of randomized controlled trials of BV during pregnancy did not find favor BV treatment in average-risk women

for any outcome of pregnancy (

). In addition, recent clinical trials did not find reduction in the incidence of premature birth or among high risk

or low risk asymptomatic pregnant women after a treatment dose of metronidazole (

). In clinical practice, high-risk asymptomatic pregnant women, usually on the screen early in the second trimester and

oral metro nidazole, but for the benefit of this therapy in reducing the risk womanBЂ ™ s premature birth remains unclear

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